What are supermolecules?

Supermolecules are nutrients shown in studies to support healthy aging processes… such as cellular energy, antioxidant defenses, and immune health.*

They…

are studied by science
have a specific dosage
are precisely sourced
researched across demographics
and support healthy aging processes

The problem with whole foods

But there is a problem.

A typical 'whole food' diet cannot provide all of these supermolecules. It would be the equivalent of consuming kilos of food and over 15,000 calories every day to reach the nutritionally comparable study-level amounts. It doesn't matter if you're a carnivore, vegan, keto, etc.

If you want study-level nutrition, you have to supplement.

But it would require taking 100+ pills daily.

We asked, "can we make it easy?"

A team of world-class doctors and scientists spent years researching. Together, we designed the world's highest-density supermolecule protocol to match the science.

Anything that tasted good = we put into a drink
Anything that tasted bad = we put into capsules

One yum drink and 2 pills. We called it 'the easy stack'.

The 36 supermolecules

A simple morning protocol with unmatched nutrition density:

Spermidine, CaAKG, Selenium, L-Glutathione, Vitamin B12 (Methylcobalamin), Potassium Iodide, Vitamin B1 (Thiamine HCl), Vitamin B3 (Niacinamide), Sodium Hyaluronate, L-Lysine, Taurine, Magnesium Citrate, Nicotinamide Riboside (NR), Folate (Calcium L-5-Methyltetrahydrofolate), Lactobacillus Acidophilus, Vitamin B6 (Pyridoxine HCI), Glycine, Vitamin C (Ascorbic Acid), Manganese Citrate, L-Theanine, Lithium Orotate, Vitamin B7 (Biotin), Boron (Glycinate), Glucoraphanin, Vitamin E (d-alpha tocopherol), Creatine Monohydrate, Vitamin D (Cholecalciferol), Luteolin, Allulose, Zinc Bisglycinate, Glucosamine, Vitamin B2 (Riboflavin), Fisetin, Vitamin B5 (D-Calcium-Pantothenate), Calcium (Carbonate + DiCalcium Phosphate), Ubiquinol

And, taken together, these supermolecules act synergistically.

For example, for immune system support, three supermolecules work together: Fisetin, Spermidine, and L-Glutathione.* The immune system is closely linked to overall health in many studies.

Or, for mitochondria support, five supermolecules work together: NR, CaAKG, Ubiquinol, Taurine & Glycine.* Their efficiency directly determines your body's overall energy and metabolic health.

When all 36 supermolecules are taken together, they form an All-Star team. Supporting key systems like cellular metabolism, antioxidant defense, structural support, mitochondrial function, and essential micronutrients.*

Quality standards

Individually, each supermolecule is meticulous:

evidence-backed
specific quantities
from a precise source
heavy-metal tested
purity tested
backed by third-party labs
priced as low-cost as possible
for all ages and genders^

This is the easy stack. And Bryan Johnson takes it daily.

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We made it simple. Whether you get these supermolecules from us or somewhere else, we don't mind. Either way, prioritize your future self.

Be well, Blueprint

Originally published in Bryan Johnson's Blueprint newsletter (November 21, 2025). This content is for informational purposes only and is not medical advice. Consult your healthcare provider before starting any new wellness protocol.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

^If pregnant, under the age of 18 years old, or have an existing health condition, please consult with a doctor first.

Can Nutrients Slow Aging?

What are supermolecules?

The problem with whole foods

The 36 supermolecules

Quality standards